Stem Cell-Enhancing Drug May Help Regenerate Damaged Teeth

It is reported that some drugs that enhance the stem cell levels in the body can purportedly help promote teeth repair, at least in mice. That is according to a study that was published on January 9 in Scientific Reports.

You see, when your tooth loses Dentin– that small, boney layer just situated underneath the enamel- the stem cells that are buried deep in the center of the tooth can actually initiate a regrowth process by repairing the damaged tissue inside.

In normal situations, this repair mechanism actually works as a means to repair small cracks and cavities. However, Paul Sharpe and his medical team at King’s College in London found that by applying a certain substance known as Tideglusib, a medication that can help treat people with Alzheimer’s disease can actually enhance this process, thus improving the results that you’re getting.

Sharpe told the Guardian that almost every one of us has or may experience some tooth decay in our lifetime. In fact, 9 out of 10 people suffer from it, but the good thing is that it is a very treatable condition. He and his team were able to create something that is simple, cheap, and quick to apply.

The Study

The research was done on laboratory mice. The tiny teeth of the mice were drilled and they filled the cavities with some sort of biodegradable sponge that was soaked in Tideglusib.

After six weeks, they’ve discovered that the treatment had actually helped the mice replenish and regrow their dentin in the affected teeth. The researchers would create subsequent studies to test whether the treatment can be replicated and be done on human teeth as well. Current findings are quite promising.

According to Vanessa Chrepa, a researcher at the University of Washington, Sharpe and his team took some really important steps in helping to create a useful solution for people who suffer from cavities. The procedure that was done may help create an avenue to come up with other suitable treatments for various medical conditions as well.

Not All Too Surprising

A lot of studies have already suggested that stem cells do have the ability to help regrow, replenish, or recreate something that was damaged or destroyed due to a medical illness, trauma, or other human conditions.

By harnessing its power, Sharpe and his team were able to regrow the mice’s teeth, provided that they give ample time for the stem cells to do their thing.

Who knows, other scientists might get some notes from his research and would then use it to create a cure for something else.